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MEDICATION guide
Nicotine Replacement Therapy

Specifics on the Nicotine Inhaler

Dosing:
The initial dosage is individualized--people may self-dose to the level of nicotine they require. The best effect is achieved by frequent, continuous puffing for 20 minutes. One cartridge will last for 20 minutes of continuous puffing and deliver 4 mg of nicotine; only 2 mg are actually absorbed. This is the equivalent of about 2 cigarettes. The maximum suggested dose is 16 cartridges/day.

Product Strengths:
The nicotine inhaler addresses pharmacological, behavioral & sensory stimuli aspects of smoking. Also, the potential for abuse is no greater than with nicotine gum, since the effects on the user are generally the same.

Manufacturer's Recommended Treatment Duration:
Manufacturers report and research has shown that the most successful quitters use 6-16 cartridges/day for the initial treatment period of 12 weeks, followed by gradual reduction of dose over the next 6-12 weeks. Manufacturers recommend against using the inhaler for longer than 6 months.

Adverse Reactions:
About 40% of users experience mouth and throat irritation. Symptoms usually diminish with regular use. Some people experience upset stomachs with use of the inhaler.

Cost:
The average retail cost of the nicotine inhaler is approximately $45.00/package (42 cartridges).


Adapted with permission from materials from the Center for Tobacco Prevention & Control, Massachusetts Tobacco Control Program, Department of Public Health.


Content author: Alan S. Peters, CTTS-M
Reviewed by: Andy Perez, MD, MBA, FACEP, February 2009

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