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MEDICATION guide
Nicotine Replacement Therapy
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Comparison of Nicotine Replacement Products

NRT Form

Availability

Flexible Dosing

Min/Max Dose

Time To Onset

Oral Delivery

Primary Side Effects

Generic Form Available

Nicotine

Patch

Over-the-Counter

No

1 daily

1-3 hours

No

Topical skin rash

Yes

Nicotine Gum

Over-the-Counter

Yes

9-20 daily

7-10 mins

Yes

mouth/throat soreness

No

Nicotine Lozenge

Over-the-Counter

Yes

9-20 daily

7-10 mins

Yes

hiccups; heartburn

No

Nicotine Inhaler

Prescription

Yes

6-16 daily

5 mins

Yes

cough; throat irritation

No

Nasal Spray

Prescription

Yes

13-20 daily

10-15

mins

No

nose/throat irritation; runny nose

No

(Adapted from Schmitz J., Henningfield J, Jarvik M, "Pharmacologic Therapies for Nicotine Dependence." In Principles for Addiction Medicine, 2nd ed., 1998).


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