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MEDICATION Guide
Nicotine Replacement Therapy (NRT)

The Nicotine Lozenge and Mini Lozenge

What Is It?
The nicotine lozenge is an oral variety of NRT. The lozenge comes in a form similar to hard candy, and slowly releases nicotine in the mouth. The mini lozenge dissolves up to 3x faster than regular stop-smoking lozenges. Studies show that the nicotine lozenge is as effective as other NRT's when used as directed. Like the nicotine gum, the nicotine lozenge delivers nicotine to the brain more quickly than the patch, making it easier to tailor dosage according to need. Using the nicotine lozenge approximately doubles the likelihood of successfully quitting smoking compared to using no quit smoking medication.

How do you use the nicotine lozenge?
Simply place the lozenge in your mouth and let it dissolve, moving it back and forth from time to time. Each lozenge will last about 20-30 minutes, and nicotine will continue to absorb through the lining of the mouth for a short time after the lozenge has disappeared. It is recommended you use at least 9 lozenges per day for the first 6 weeks, and that you should talk to your doctor if you feel the need to use the lozenge for more than 12 weeks. Take care not to eat or drink 15 minutes before using the lozenge, or while it is in your mouth.

What is the dose?

  • One lozenge is one dose; the strength of the lozenge is determined by "Time to First Cigarette" (TTFC). If you typically smoked your first cigarette within 30 minutes of awakening, you should use the 4mg lozenge; more than 30 minutes to the first smoke indicates the 2mg lozenge.
  • One lozenge every 1-2 hours for the first six weeks; one lozenge every 2-4 hours during weeks 7-9; one lozenge every 4-8 hours during the final weeks 10-12.
  • Do not use more than 24 lozenges per day.

More medically specific information ...


Content author: Alan S. Peters, CTTS-M
Reviewed by: Ann Wendling, MD, MPH, April 2013

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